Nucleic Acids Research Ptasmidal maintenance of composite DNA derived from polyoma related plasmid , L factor

Abstract

Recently, we reported a multicopy mammalian plasmid with a structure related to polyoma (1). The plasmid, named L factor, was found at a high copy number (5,000 or more per cell) in a subclone derived from mouse L cells. We attempted to utilize L factor as a plasmid vector for mammalian cells. A series of composite DNA consisting of L factor and a foreign… (More)

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