Nucleic Acids Research Histone gene number in relation to C-value in amphibians

@inproceedings{Hilder2005NucleicAR,
  title={Nucleic Acids Research Histone gene number in relation to C-value in amphibians},
  author={Vaughan A. Hilder and R. Nigel Livesey and Philip C. Turner and Marcela T. Vlad},
  year={2005}
}
We have compared the number of copies of sequences complementary to a cloned Xenopus histone H4 coding sequence in the genomes of Xenopus, Triturus and Ambystoma, amphibian species with widely different C-values (3, 23 and 38pg DNA/haploid genome respectively). Quantitative autoradiography indicates that H4 sequences constitute a greater proportion of the genome the larger that genome is. Measurement of the absolute copy-number by reassociation kinetic analysis indicated 47±lo, 636±21 and 2685… CONTINUE READING