Nucleic Acids Research DNA amplification-deletion hi a spontaneous mutation of the hamster aprt locus: structure and sequence of the novel joint

I N T R O D U C T I O N G e n e a m p l i f i c a t i o n o c c u r s 1n c e l l s _1_r̂ v i v o d u r i n g t h e c o u r s e of d e v e l o p m e n t ( 1 , 2 ) or t u m o u r f o r m a t i o n ( 3 5 ) and j_n_ v i t r o as d e t e c t e d 1n d r u g r e s i s t a n t c e l l p o p u l a t i o n s ( 6 8 ) . D e s p i t e t h e w i d e s p r e a d o c c u r… CONTINUE READING