Nucleator-dependent intercellular assembly of adhesive curli organelles in Escherichia coli.

@article{Hammar1996NucleatordependentIA,
  title={Nucleator-dependent intercellular assembly of adhesive curli organelles in Escherichia coli.},
  author={Marten Hammar and Zhao Lian Bian and Staffan J. Normark},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1996},
  volume={93 13},
  pages={6562-6}
}
Bacterial adhesion to other bacteria, to eukaryotic cells, and to extracellular matrix proteins is frequently mediated by cell surface-associated polymers (fimbriae) consisting of one or more subunit proteins. We have found that polymerization of curlin to fimbriae-like structures (curli) on the surface of Escherichia coli markedly differs from the prevailing model for fimbrial assembly in that it occurs extracellularly through a self-assembly process depending on a specific nucleator protein… CONTINUE READING
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