Nuclear transport of baculovirus: revealing the nuclear pore complex passage.

@article{Au2012NuclearTO,
  title={Nuclear transport of baculovirus: revealing the nuclear pore complex passage.},
  author={Shelly Au and Nelly Pant{\'e}},
  journal={Journal of structural biology},
  year={2012},
  volume={177 1},
  pages={
          90-8
        }
}
Baculoviruses are one of the largest viruses that replicate in the nucleus of their host cells. During an infection the capsid, containing the DNA viral genome, is released into the cytoplasm and delivers the genome into the nucleus by a mechanism that is largely unknown. Here, we used capsids of the baculovirus Autographa californica multiple nucleopolyhedrovirus in combination with electron microscopy and discovered this capsid crosses the NPC and enters into the nucleus intact, where it… CONTINUE READING

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