Nuclear size measurement for distinguishing urothelial carcinomas from reactive urothelium on tissue sections

@inproceedings{Poropatich2016NuclearSM,
  title={Nuclear size measurement for distinguishing urothelial carcinomas from reactive urothelium on tissue sections},
  author={Kate Poropatich and Jason C. Yang and Rajen Goyal and Vamsi Parini and Ximing J. Yang},
  booktitle={Diagnostic pathology},
  year={2016}
}
BACKGROUND Pathological diagnosis of urothelial carcinoma (UC) is primarily based on cytological atypia. It has previously been shown that high-grade (HG) UC, particularly UC in situ cells (CIS), can be over five times the size of a lymphocyte. However, this has not been demonstrated in comparison to reactive urothelium. The objective of this study was to empirically compare the difference in nuclear size of UC cells with reactive urothelial cells. METHODS Using CellSens imaging software, we… CONTINUE READING