Nuclear shape, mechanics, and mechanotransduction.

Abstract

In eukaryotic cells, the nucleus contains the genome and is the site of transcriptional regulation. The nucleus is the largest and stiffest organelle and is exposed to mechanical forces transmitted through the cytoskeleton from outside the cell and from force generation within the cell. Here, we discuss the effect of intra- and extracellular forces on… (More)
DOI: 10.1161/CIRCRESAHA.108.173989

Topics

Cite this paper

@article{Dahl2008NuclearSM, title={Nuclear shape, mechanics, and mechanotransduction.}, author={Kris Noel Dahl and Alexandre J. S. Ribeiro and Jan Lammerding}, journal={Circulation research}, year={2008}, volume={102 11}, pages={1307-18} }