Nuclear reprogramming: A key to stem cell function in regenerative medicine

  title={Nuclear reprogramming: A key to stem cell function in regenerative medicine},
  author={Jason H. Pomerantz and Helen M. Blau},
  journal={Nature Cell Biology},
The goal of regenerative medicine is to restore form and function to damaged tissues. One potential therapeutic approach involves the use of autologous cells derived from the bone marrow (bone marrow-derived cells, BMDCs). Advances in nuclear transplantation, experimental heterokaryon formation and the observed plasticity of gene expression and phenotype reported in multiple phyla provide evidence for nuclear plasticity. Recent observations have extended these findings to show that endogenous… CONTINUE READING
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Evidence of a pluripotent human embryonic stem cell line derived from a cloned blastocyst

  • Hwang, S W.
  • Science 303,
  • 2004

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