Nuclear receptors in cancer — uncovering new and evolving roles through genomic analysis

Abstract

Nuclear receptors (NRs) have historically been at the forefront of cancer research, where they are known to act as critical regulators of disease. They also serve as biomarkers for tumour subclassification and targets for hormone therapy. However, most tumour types express extensive repertoires of NRs, whose interactions provide multiple paths for disease… (More)
DOI: 10.1038/nrg.2017.102

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