Nuclear receptors and AMPK: resetting metabolism.

  title={Nuclear receptors and AMPK: resetting metabolism.},
  author={Weiwei Fan and Michael Downes and Ayelet Atkins and Renyi Yu and Ronald M Evans},
  journal={Cold Spring Harbor symposia on quantitative biology},
Obesity, and in particular central adiposity, is a key feature of metabolic syndrome, which includes trends toward increased triglycerides, insulin resistance, high blood pressure, hypercholesterolemia, and heart disease. It has a prevalence of 25% or more and is a dominant component of the health care budgets in Western societies. In addition to genetic causes, high-fat diets and disrupted sleep patterns have major influences on the development of metabolic syndrome. Recent studies have… CONTINUE READING

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