Nuclear receptor coactivators and corepressors.

@article{Horwitz1996NuclearRC,
  title={Nuclear receptor coactivators and corepressors.},
  author={K B Horwitz and Twila A. Jackson and David L. Bain and Jennifer K Richer and Glenn S Takimoto and Lin Tung},
  journal={Molecular endocrinology},
  year={1996},
  volume={10 10},
  pages={1167-77}
}
The nuclear receptors belong to a superfamily of proteins, many of which are ligand-regulated, that bind to specific DNA sequences and control specific gene transcription. Recent data show that, in addition to contacting the basal transcription machinery directly, nuclear receptors inhibit or enhance transcription by recruiting an array of coactivator or corepressor proteins to the transcription complex. In this review we define the properties of these putative coregulatory factors; we describe… CONTINUE READING

From This Paper

Topics from this paper.

Citations

Publications citing this paper.
Showing 1-10 of 239 extracted citations

Specificity of thyroid hormone receptor subtype and steroid receptor coactivator-1 on thyroid hormone action.

American journal of physiology. Endocrinology and metabolism • 2003
View 4 Excerpts
Highly Influenced

Similar Papers

Loading similar papers…