Nuclear receptor coactivator function in reproductive physiology and behavior.

  title={Nuclear receptor coactivator function in reproductive physiology and behavior.},
  author={Heather A Molenda and Caitlin P Kilts and Rachel Louise Allen and Marc J Tetel},
  journal={Biology of reproduction},
  volume={69 5},
Gonadal steroid hormones act throughout the body to elicit changes in gene expression that result in profound effects on reproductive physiology and behavior. Steroid hormones exert many of these effects by binding to their respective intracellular receptors, which are members of a nuclear receptor superfamily of transcriptional activators. A variety of in vitro studies indicate that nuclear receptor coactivators are required for efficient transcriptional activity of steroid receptors. Many of… CONTINUE READING


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