Nuclear pore complex glycoproteins contain cytoplasmically disposed O- linked N-acetylglucosamine

  title={Nuclear pore complex glycoproteins contain cytoplasmically disposed O- linked N-acetylglucosamine},
  author={G. D. Holt and Christine M. Snow and A M Senior and Robert S. Haltiwanger and Larry Gerace and Gerald W. Hart},
  journal={The Journal of Cell Biology},
  pages={1157 - 1164}
A novel form of protein-saccharide linkage consisting of single N-acetylglucosamine (GlcNAc) residues attached in O-linkages directly to the polypeptide backbone has been described (Holt, G. D., and G. W. Hart, 1986, J. Biol. Chem., 261:8049-8057). This modification was found on proteins distributed throughout the cell, although proteins bearing O-linked GlcNAc moieties were particularly abundant in the cytosolic and nuclear envelope fractions of rat liver. In the accompanying article (Snow, C… CONTINUE READING


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