Nuclear phosphoproteins HMGA and their relationship with chromatin structure and cancer

@article{Sgarra2004NuclearPH,
  title={Nuclear phosphoproteins HMGA and their relationship with chromatin structure and cancer},
  author={R. Sgarra and A. Rustighi and M. Tessari and Julie Di Bernardo and S. Altamura and A. Fusco and G. Manfioletti and V. Giancotti},
  journal={FEBS Letters},
  year={2004},
  volume={574}
}
  • R. Sgarra, A. Rustighi, +5 authors V. Giancotti
  • Published 2004
  • Biology, Medicine
  • FEBS Letters
  • The structural characteristics of the three nuclear phosphoproteins of the high mobility group A family are outlined and related to their participation in chromatin structure alteration in many biological processes such as gene expression, neoplastic transformation, differentiation, and apoptosis. The elevated expression of these proteins in tumor cells and their post‐translational modifications, such as phosphorylation, acetylation and methylation, are discussed and suggested as suitable… CONTINUE READING
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