Nuclear phosphatase PPM1G in cellular survival and neural development.

@article{Foster2013NuclearPP,
  title={Nuclear phosphatase PPM1G in cellular survival and neural development.},
  author={William H Foster and Adam D Langenbacher and Chen Gao and Jaunian Chen and Yibin Wang},
  journal={Developmental dynamics : an official publication of the American Association of Anatomists},
  year={2013},
  volume={242 9},
  pages={1101-9}
}
BACKGROUND PPM1G is a nuclear localized serine/threonine phosphatase implicated to be a regulator of chromatin remodeling, mRNA splicing, and DNA damage. However, its in vivo function is unknown. RESULTS Here we show that ppm1g expression is highly enriched in the central nervous system during mouse and zebrafish development. ppm1g(-/-) mice were… CONTINUE READING