Nuclear matrix associated protein PML: an arsenic trioxide apoptosis therapeutic target protein in HepG2 cells.

Abstract

OBJECTIVE To investigate arsenic trioxide (As(2)O(3))-induced apoptosis and the effects on cell nuclear matrix related protein promyelocytic leukaemia (PML). METHODS HepG2 cells were cultured in MEM medium and treated with 0.5, 2, 5 and 10 micro mol/L As(2)O(3) for either 24 h or 96 h at each concentration. In situ terminal deoxynucleotidyl transferase… (More)

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@article{Yu2003NuclearMA, title={Nuclear matrix associated protein PML: an arsenic trioxide apoptosis therapeutic target protein in HepG2 cells.}, author={Ding - Li Yu and Zihui Wang and Liyuan Zhu and E. C. Chew}, journal={Chinese medical journal}, year={2003}, volume={116 1}, pages={93-8} }