Nuclear localization of the testis determining gene product SRY

  • Xavier Rebil
  • Published 1995 in The Journal of Cell Biology


We have studied the expression of the human SRY protein (termed p27SRY) in two different cell lines by using specific antibodies. Confocal microscopy enabled us to localize p27SRY precisely in the nucleus in a discrete punctuate pattern. Furthermore, through microinjection experiments, we have demonstrated that the localization of the p27SRY protein into… (More)


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