Nuclear localization of beta-catenin involved in precancerous change in oral leukoplakia

@article{Ishida2007NuclearLO,
  title={Nuclear localization of beta-catenin involved in precancerous change in oral leukoplakia},
  author={Kosei Ishida and Satoshi Ito and Naoyuki Wada and Hiroyo Deguchi and Tsuyoshi Hata and Masaru Hosoda and Tsutomu Nohno},
  journal={Molecular Cancer},
  year={2007},
  volume={6},
  pages={62 - 62}
}
Oral leukoplakia is a precancerous change developed in the oral mucosa, and the mechanism that oral leukoplakia becomes malignant through atypical epithelium is not known. Here we compared the β-catenin expression detected by immunohistochemical staining in the normal oral epithelium and in the oral leukoplakia with or without dysplasia. The normal oral epithelium showed β-catenin expression only in the cell membrane, but not in the nuclei. In the oral leukoplakia without dysplasia, 7 out of 17… CONTINUE READING

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β-Catenin signaling

  • H Li, R Pamukcu, WJ Thompson
  • Cancer Biol Ther
  • 2002
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