Nuclear localisation of p65 in sputum macrophages but not in sputum neutrophils during COPD exacerbations.

@article{Caramori2003NuclearLO,
  title={Nuclear localisation of p65 in sputum macrophages but not in sputum neutrophils during COPD exacerbations.},
  author={Gaetano Caramori and Micaela Romagnoli and Paolo Casolari and Cinzia Maria Bellettato and George Casoni and Piera Boschetto and Kian Fan Chung and Peter J Barnes and Ian M. Adcock and Adalberto Ciaccia and Alberto Papi},
  journal={Thorax},
  year={2003},
  volume={58 4},
  pages={
          348-51
        }
}
BACKGROUND Exacerbations represent an important feature of the clinical manifestation and natural history of chronic obstructive pulmonary disease (COPD). Nuclear localisation of p65 is a signal of nuclear factor-kappaB (NF-kappaB) activation. A study was undertaken to evaluate whether NF-kappaB activation is modified in sputum cells during COPD exacerbations. METHODS Total and nuclear p65 immunoreactivity was measured by immunocytochemistry in the sputum cells of 11 smokers with moderate… CONTINUE READING

Citations

Publications citing this paper.
SHOWING 1-10 OF 85 CITATIONS, ESTIMATED 51% COVERAGE

169 Citations

051015'03'06'10'14'18
Citations per Year
Semantic Scholar estimates that this publication has 169 citations based on the available data.

See our FAQ for additional information.

References

Publications referenced by this paper.
SHOWING 1-9 OF 9 REFERENCES

Glucocorticoid receptor immunolocalisation in sputum cells

  • OS Usmani, K Maneechotesuwan, K Tomita
  • Am J Respir Crit Care Med
  • 1995

Similar Papers

Loading similar papers…