Nuclear inositol lipids. Relationship between growth factor induced metabolic changes and protein kinase C activity.

@article{Cocco1990NuclearIL,
  title={Nuclear inositol lipids. Relationship between growth factor induced metabolic changes and protein kinase C activity.},
  author={L. Cocco and S. Capitani and A. Martelli and R. F. Irvine and R. Gilmour and N. Maraldi and O. Barnabei and F. Manzoli},
  journal={Advances in enzyme regulation},
  year={1990},
  volume={30},
  pages={
          155-72
        }
}
We have sought to establish the effect of mitogen treatment on nuclear inositol lipids and the relationship between inositol cycle products and hyperphosphorylation of nuclear proteins via PKC during the lag phase leading to the onset of DNA synthesis. Swiss 3T3 cells were labelled for 36 hr with high levels of [3H]-myo-inositol and the radioactivity in nuclear inositol phospholipids was measured. Treatment of cells for 2 min, but not for 4 hr, with mitogenic concentrations of insulin-like… Expand
11 Citations
Inositol lipid phosphorylation in the cell nucleus.
Topology of inositol lipid signal transduction in the nucleus
Nuclear phosphoinositidase C during growth factor stimulation.
Intermediate filament proteins: cytoskeletal elements with gene-regulatory function?
...
1
2
...

References

SHOWING 1-10 OF 56 REFERENCES
Lipid mediated signal transduction in the cell nucleus.
Phosphorylation of lamin B at the nuclear membrane by activated protein kinase C.
Rapid activation of protein kinase C in isolated rat liver nuclei by prolactin, a known hepatic mitogen.
...
1
2
3
4
5
...