Nuclear import of DNA repair proteins.

@article{Boulikas1997NuclearIO,
  title={Nuclear import of DNA repair proteins.},
  author={Teni Boulikas},
  journal={Anticancer research},
  year={1997},
  volume={17 2A},
  pages={843-63}
}
DNA repair enzymes play a pivotal role in the maintenance of chromosome integrity and in the elimination of premutagenic lesions from DNA by patrolling the genome; nuclear import mechanisms are implicated in molecular carcinogenesis. We have attempted to predict cell trafficking and the nuclear importation of proteins involved in DNA repair by sequence analysis aimed at identifying karyophilic clusters (arginines, lysines, histidines) flanked by the helix breakers proline or glycine that could… CONTINUE READING

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