Nuclear import and export of influenza virus nucleoprotein.

@article{Neumann1997NuclearIA,
  title={Nuclear import and export of influenza virus nucleoprotein.},
  author={Guillermo Neumann and Maria Rita Castrucci and Yoshihiro Kawaoka},
  journal={Journal of virology},
  year={1997},
  volume={71 12},
  pages={
          9690-700
        }
}
Influenza virus nucleoprotein (NP) shuttles between the nucleus and the cytoplasm. A nuclear localization signal (NLS) has been identified in NP at amino acids 327 to 345 (J. Davey et al., Cell 40:667-675, 1985). However, some NP mutants that lack this region still localize to the nucleus, suggesting an additional NLS in NP. We therefore investigated the nucleocytoplasmic transport of NP from influenza virus A/WSN/33 (H1N1). NP deletion constructs lacking the 38 N-terminal amino acids, as well… CONTINUE READING
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