Nuclear hormone receptors as regulators of the renin-angiotensin-aldosterone system.

  title={Nuclear hormone receptors as regulators of the renin-angiotensin-aldosterone system.},
  author={Irma Kuipers and Pim van der Harst and Gerjan Navis and Linda van Genne and Fulvio Morello and Wiek H van Gilst and Dirk Jan van Veldhuisen and Rudolf A de Boer},
  volume={51 6},
The renin-angiotensin-aldosterone system (RAAS) has been identified as the main system involved in blood pressure regulation, renal hemodynamics, and sodiumvolume homeostasis. Furthermore, the RAAS directly affects vascular and cardiac remodeling through proliferative and inflammatory signaling. Pharmacological targeting of the RAAS is a consolidated and evidence-based approach in the treatment of various aspects of cardiovascular disease. An exploding number of recent studies have provided… CONTINUE READING

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