Nuclear hormone receptors and gene expression.

  title={Nuclear hormone receptors and gene expression.},
  author={Ana Aranda and {\'A}. Pascual},
  journal={Physiological reviews},
  volume={81 3},
The nuclear hormone receptor superfamily includes receptors for thyroid and steroid hormones, retinoids and vitamin D, as well as different "orphan" receptors of unknown ligand. Ligands for some of these receptors have been recently identified, showing that products of lipid metabolism such as fatty acids, prostaglandins, or cholesterol derivatives can regulate gene expression by binding to nuclear receptors. Nuclear receptors act as ligand-inducible transcription factors by directly… 

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