Nuclear heat shock response and novel nuclear domain 10 reorganization in respiratory syncytial virus-infected a549 cells identified by high-resolution two-dimensional gel electrophoresis.

@article{Brasier2004NuclearHS,
  title={Nuclear heat shock response and novel nuclear domain 10 reorganization in respiratory syncytial virus-infected a549 cells identified by high-resolution two-dimensional gel electrophoresis.},
  author={Allan R. Brasier and Heidi Spratt and Zheng Wu and Istvan Boldogh and Yuhong Zhang and Roberto P Garofalo and Antonella Casola and Jawad Pashmi and Anthony Haag and Bruce Luxon and Alexander Kurosky},
  journal={Journal of virology},
  year={2004},
  volume={78 21},
  pages={11461-76}
}
The pneumovirus respiratory syncytial virus (RSV) is a leading cause of epidemic respiratory tract infection. Upon entry, RSV replicates in the epithelial cytoplasm, initiating compensatory changes in cellular gene expression. In this study, we have investigated RSV-induced changes in the nuclear proteome of A549 alveolar type II-like epithelial cells by… CONTINUE READING