Nuclear functions of heterogeneous nuclear ribonucleoproteins A/B

  title={Nuclear functions of heterogeneous nuclear ribonucleoproteins A/B},
  author={Yaowu He and Ross Flewell Smith},
  journal={Cellular and Molecular Life Sciences},
The hnRNP A/B proteins are among the most abundant RNA-binding proteins, forming the core of the ribonucleoprotein complex that associates with nascent transcripts in eukaryotic cells. There are several paralogs in this subfamily, each of which is subject to alternative transcript splicing and post-translational modifications. The structural diversity of these proteins generates a multitude of functions that involve interactions with DNA or, more commonly, RNA. They also recruit regulatory… CONTINUE READING


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