Nuclear features of infiltrating urothelial carcinoma are distinguished from low-grade noninvasive papillary urothelial carcinoma by image analysis

@article{Kosuge2017NuclearFO,
  title={Nuclear features of infiltrating urothelial carcinoma are distinguished from low-grade noninvasive papillary urothelial carcinoma by image analysis},
  author={Noritake Kosuge and Masanao Saio and Hirofumi Matsumoto and Hajime Aoyama and Akiko Matsuzaki and Naoki Yoshimi},
  journal={Oncology Letters},
  year={2017},
  volume={14},
  pages={2715 - 2722}
}
Recent advances in computer technology have been made and image analysis (IA) has been introduced into pathological fields. The present study aimed to investigate the utility of IA for the evaluation of nuclear features and staining of immunohistochemistry (IHC) for Ki-67, p53 and GATA-binding protein 3 (GATA-3) in urothelial carcinoma tissue samples. A total of 49 cases of urothelial carcinoma tissue samples were obtained by transurethral resection of bladder tumors, which included 11 low… 
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