Nuclear factor of activated T cells is associated with a mast cell interleukin 4 transcription complex.

@article{Weiss1996NuclearFO,
  title={Nuclear factor of activated T cells is associated with a mast cell interleukin 4 transcription complex.},
  author={David L. Weiss and John A Hural and David Tara and Luika A. Timmerman and Greg W. Henkel and Melissa A Brown},
  journal={Molecular and cellular biology},
  year={1996},
  volume={16 1},
  pages={228-35}
}
Interleukin 4 (IL-4), an immunoregulatory cytokine, is produced only by a subset of activated T cells and cells of the mast cell-basophil lineage. The production of IL-4 by mast cells likely represents a significant source of this protein in local immune-inflammatory responses in the skin, brain, gastrointestinal, and respiratory tracts, in which mast cells are prevalent. In the present study, the cis- and trans-acting elements that control inducible mast cell IL-4 gene transcription were… CONTINUE READING

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