Nuclear factor kappaB is activated in macrophages and epithelial cells of inflamed intestinal mucosa.

@article{Rogler1998NuclearFK,
  title={Nuclear factor kappaB is activated in macrophages and epithelial cells of inflamed intestinal mucosa.},
  author={Gerhard Rogler and Korbinian Brand and Daniela Vogl and Simon Page and Robert R Hofmeister and Tilo Andus and Ruth Knuechel and Patrick A. Baeuerle and Juergen Schoelmerich and Volker Gro\ss},
  journal={Gastroenterology},
  year={1998},
  volume={115 2},
  pages={357-69}
}
BACKGROUND & AIMS Transcription factors of the nuclear factor kappaB (NF-kappaB) family play an important role in the regulation of genes involved in inflammation. In inflammatory bowel diseases, proinflammatory cytokines known to be regulated by NF-kappaB are involved. The aim of this study was to investigate the role of NF-kappaB activation during mucosal inflammation in situ. METHODS A monoclonal antibody, alpha-p65mAb, was applied for immunofluorescence and immunohistochemical analysis… CONTINUE READING
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