Nuclear factor-kappa B contributes to excitotoxin-induced apoptosis in rat striatum.

@article{Qin1998NuclearFB,
  title={Nuclear factor-kappa B contributes to excitotoxin-induced apoptosis in rat striatum.},
  author={Z H Qin and Yongfu Wang and Masatsugu Nakai and Thomas N. Chase},
  journal={Molecular pharmacology},
  year={1998},
  volume={53 1},
  pages={33-42}
}
Excitotoxin-induced destruction of striatal neurons, proposed as a model of Huntington's disease, involves a process having the biochemical stigmata of apoptosis. Recent studies suggested that transcription factor nuclear factor (NF)-kappa B may be involved in excitotoxicity. To further analyze the contribution of NF kappa B to excitotoxic neuronal death in vivo, changes in binding activities of NF kappa B and other transcription factors as well as the consequences of inhibiting NF kappa B… CONTINUE READING
59 Citations
44 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 59 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 44 references

Apoptosis : activation NFk B or die ?

  • AA Beg, D Baltimore
  • Curr Biol
  • 1996
Highly Influential
5 Excerpts

Similar Papers

Loading similar papers…