Nuclear factor kappa B--molecular biomedicine: the next generation.

  title={Nuclear factor kappa B--molecular biomedicine: the next generation.},
  author={Peter Celec},
  journal={Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie},
  volume={58 6-7},
  • Peter Celec
  • Published 2004 in
    Biomedicine & pharmacotherapy = Biomedecine…
Nuclear factor kappa B (NFkappaB) as a transcription factor plays an important integrating role in the intracellular regulation of immune response, inflammation and cell cycle regulation. Nouvelle insights into the structure and regulation of activation of NFkappaB have brought a detailed picture of the function of this transcription factor. In this review the findings of interactions of NFkappaB with its inhibitors, tumour necrosis factor alpha and glucocorticoids are presented. The results… CONTINUE READING

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