Nuclear factor kappa B (NF-κB) in multiple sclerosis pathology.


The nuclear factor kappa B (NF-κB) signaling cascade plays a critical role in the regulation of immune and inflammatory responses and has been implicated in the pathogenesis of autoimmune demyelinating diseases such as multiple sclerosis (MS) and experimental autoimmune encephalomyelitis (EAE), the main animal model of MS. NF-κB is essential for peripheral… (More)
DOI: 10.1016/j.molmed.2013.08.001


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@article{Guire2013NuclearFK, title={Nuclear factor kappa B (NF-κB) in multiple sclerosis pathology.}, author={Conor Mc Guire and Marco Prinz and Rudi Beyaert and Geert van Loo}, journal={Trends in molecular medicine}, year={2013}, volume={19 10}, pages={604-13} }