Nuclear factor-erythroid 2-related factor 2 as a chemopreventive target in colorectal cancer.

@article{Saw2011NuclearF2,
  title={Nuclear factor-erythroid 2-related factor 2 as a chemopreventive target in colorectal cancer.},
  author={Constance Lay Lay Saw and A N Tony Kong},
  journal={Expert opinion on therapeutic targets},
  year={2011},
  volume={15 3},
  pages={
          281-95
        }
}
INTRODUCTION Numerous epidemiological studies have linked consumption of cruciferous vegetables to a reduced risk of colorectal cancer (CRC) in individuals. It is currently well accepted that chronic inflammation is a contributing factor in 15 - 20% malignancies including CRC. Many chemopreventive compounds are effective in preclinical systems and many ongoing clinical trials are showing promising findings. Many of these compounds could activate the antioxidant responsive element (ARE), a… CONTINUE READING
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