Nuclear expression of N-cadherin correlates with poor prognosis of nasopharyngeal carcinoma.

@article{Luo2012NuclearEO,
  title={Nuclear expression of N-cadherin correlates with poor prognosis of nasopharyngeal carcinoma.},
  author={Wei-ren Luo and Ai-bing Wu and Wei-yi Fang and Si-yi Li and Kai-Tai Yao},
  journal={Histopathology},
  year={2012},
  volume={61 2},
  pages={
          237-46
        }
}
AIMS To investigate the aberrant expression of N-cadherin in nasopharyngeal carcinoma (NPC) and its prognostic significance. METHODS AND RESULTS Immunohistochemical staining for N-cadherin protein was performed on tissue microarray (TMA) from 122 NPC patients. Cytoplasmic N-cadherin was observed in 42.6% and nuclear N-cadherin in 45.1% of NPC tissues. High expression of cytoplasmic and nuclear N-cadherin was associated with a majority of the clinicopathological variables, including lymph node… CONTINUE READING

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