Nuclear expression of β-catenin and stem cell markers as potential prognostic indicators in medulloblastoma.

@article{Gowda2012NuclearEO,
  title={Nuclear expression of β-catenin and stem cell markers as potential prognostic indicators in medulloblastoma.},
  author={Kiran Krishne Gowda and Kirti Gupta and Rakesh Kapoor and Rakesh kumar Vasishta},
  journal={Neurology India},
  year={2012},
  volume={60 5},
  pages={487-94}
}
AIMS To study the prognostic role of β-catenin and stem cell markers in medulloblastoma (MB). MATERIALS AND METHODS Sixty cases of MB were retrospectively analyzed to study the expression of β-catenin, CD15, and CD133 by immunohistochemistry. Their expression was correlated with histological subtypes and event-free survival (EFS). Patients were divided into Group 1 and 2 based on non-occurrence and occurrence of events during the follow-up period. RESULTS Fifty of the 60 cases were of… CONTINUE READING

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