Nuclear dots: actors on many stages.

  title={Nuclear dots: actors on many stages.},
  author={Thomas Sternsdorf and T Gr{\"o}tzinger and Kirsten Gadgaard Jensen and H. Will},
  volume={198 1-3},
Nuclear dots (NDs), alternatively designated nuclear bodies (NBs), PML oncogenic domains (PODs), nuclear domain 10 (ND10) or Kr-bodies, became a major topic for researchers in many fields only recently. Originally described as an autoantigenic target in patients with primary biliary cirrhosis, they are now also known to play a role in development of acute promyelocytic leukemia (APL) and possibly other forms of neoplasia. Size, number and composition of NDs are regulated throughout the cell… CONTINUE READING


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