Nuclear and extra-nuclear effects of retinoid acid receptors: how they are interconnected.


The nuclear retinoic acid receptors (RAR α, β and γ) and their isoforms are ligand-dependent regulators of transcription Transcription , which mediate the effects of all-trans retinoic acid (RA), the active endogenous metabolite of Vitamin A. They heterodimerize with Retinoid X Receptors (RXRs α, β and γ), and regulate the expression of a battery of target… (More)
DOI: 10.1007/978-94-017-9050-5_6


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