Nuclear and cytoplasmic death receptor 5 as prognostic factors in patients with non-small cell lung cancer treated with chemotherapy.

Abstract

BACKGROUND Death receptor 4 (DR4) and death receptor 5 (DR5) are tumor necrosis factor-related apoptosis-inducing ligand (Apo2L/TRAIL) receptors that activate apoptosis via the extrinsic apoptosis pathway. DcR1 and DcR2 are decoy receptors for TRAIL that act antagonistically. Intracellular trafficking of TRAIL receptors has been described, but the role of… (More)
DOI: 10.1016/j.lungcan.2008.10.015

Topics

Cite this paper

@article{Leithner2009NuclearAC, title={Nuclear and cytoplasmic death receptor 5 as prognostic factors in patients with non-small cell lung cancer treated with chemotherapy.}, author={Katharina Leithner and Elvira Stacher and Robert M Wurm and Ferdinand Ploner and Franz Quehenberger and Christoph Wohlkoenig and Zolt{\'a}n B{\'a}lint and Jana Polachova and Andrea Olschewski and Hellmut Samonigg and Helmut H Popper and Horst Olschewski}, journal={Lung cancer}, year={2009}, volume={65 1}, pages={98-104} }