Nuclear activity of MLA immune receptors links isolate-specific and basal disease-resistance responses.

@article{Shen2007NuclearAO,
  title={Nuclear activity of MLA immune receptors links isolate-specific and basal disease-resistance responses.},
  author={Qianhua Shen and Yusuke Saijo and Stefan Mauch and Christoph Biskup and St{\'e}phane Bieri and Beat Keller and Hikaru Seki and Bekir Ulker and Imre E Somssich and Paul Schulze-Lefert},
  journal={Science},
  year={2007},
  volume={315 5815},
  pages={1098-103}
}
Plant immune responses are triggered by pattern recognition receptors that detect conserved pathogen-associated molecular patterns (PAMPs) or by resistance (R) proteins recognizing isolate-specific pathogen effectors. We show that in barley, intracellular mildew A (MLA) R proteins function in the nucleus to confer resistance against the powdery mildew fungus. Recognition of the fungal avirulence A10 effector by MLA10 induces nuclear associations between receptor and WRKY transcription factors… CONTINUE READING
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