Nuclear YB-1 expression as a negative prognostic marker in nonsmall cell lung cancer.


The human Y-box binding protein, YB-1, is a multifunctional protein that regulates gene expression. Nuclear expression of YB-1 has been associated with chemoresistance and poor prognosis of tumour patients. Representative samples from autopsied material of primary tumours from 77 patients with NSCLC were investigated by immunohistochemistry for subcellular… (More)


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Citations per Year

Citation Velocity: 6

Averaging 6 citations per year over the last 3 years.

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