Nuclear Receptor Corepressor 1 Expression and Output Declines with Prostate Cancer Progression.

Abstract

PURPOSE Castration therapy in advanced prostate cancer eventually fails and leads to the development of castration-resistant prostate cancer (CRPC), which has no cure. Characteristic features of CRPC can be increased androgen receptor (AR) expression and altered transcriptional output. We investigated the expression of nuclear receptor corepressor 1 (NCOR1… (More)
DOI: 10.1158/1078-0432.CCR-15-1983

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