Nuclear Mechanics and Stem Cell Differentiation

@article{Mao2015NuclearMA,
  title={Nuclear Mechanics and Stem Cell Differentiation},
  author={Xinjian Mao and N{\'u}ria Gavara and G. I. Song},
  journal={Stem Cell Reviews and Reports},
  year={2015},
  volume={11},
  pages={804-812}
}
Stem cells are characterized by their self-renewal and multi-lineage differentiation potential. Stem cell differentiation is a prerequisite for the application of stem cells in regenerative medicine and clinical therapy. In addition to chemical stimulation, mechanical cues play a significant role in regulating stem cell differentiation. The integrity of mechanical sensors is necessary for the ability of cells to respond to mechanical signals. The nucleus, the largest and stiffest cellular… CONTINUE READING
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