Nuclear Matrix Protein (NRP/B) Modulates the Nuclear Factor (Erythroid-derived 2)-related 2 (NRF2)-dependent Oxidative Stress Response*

@article{Seng2010NuclearMP,
  title={Nuclear Matrix Protein (NRP/B) Modulates the Nuclear Factor (Erythroid-derived 2)-related 2 (NRF2)-dependent Oxidative Stress Response*},
  author={S. Seng and H. Avraham and G. Birrane and Shuxian Jiang and S. Avraham},
  journal={The Journal of Biological Chemistry},
  year={2010},
  volume={285},
  pages={26190 - 26198}
}
Reactive molecules have diverse effects on cells and contribute to several pathological conditions. Cells have evolved complex protective systems to neutralize these molecules and restore redox homeostasis. Previously, we showed that association of nuclear factor (NF)-erythroid-derived 2 (E2)-related factor 2 (NRF2) with the nuclear matrix protein NRP/B was essential for the transcriptional activity of NRF2 target genes in tumor cells. The present study demonstrates the molecular mechanism by… Expand
Bardoxolone methyl analog attenuates proteinuria-induced tubular damage by modulating mitochondrial function
  • H. Nagasu, Yuji Sogawa, +10 authors N. Kashihara
  • Chemistry, Medicine
  • FASEB journal : official publication of the Federation of American Societies for Experimental Biology
  • 2019
Aldo–keto reductases mediate constitutive and inducible protection against aldehyde toxicity in human neuroblastoma SH-SY5Y cells
ENC1 Modulates the Aggregation and Neurotoxicity of Mutant Huntingtin Through p62 Under ER Stress
...
1
2
...

References

SHOWING 1-10 OF 41 REFERENCES
Nrf2-Keap1 defines a physiologically important stress response mechanism.
Nrf2, a multi‐organ protector?
The Keap1 BTB/POZ Dimerization Function Is Required to Sequester Nrf2 in Cytoplasm*
...
1
2
3
4
5
...