Nuclear Kaiso Expression Is Associated with High Grade and Triple-Negative Invasive Breast Cancer

@inproceedings{Vermeulen2012NuclearKE,
  title={Nuclear Kaiso Expression Is Associated with High Grade and Triple-Negative Invasive Breast Cancer},
  author={Jeroen F. Vermeulen and Robert A H van de Ven and Cigdem Ercan and Petra van der Groep and Ernst Evert van der Wall and Peter Bult and Matthias Christgen and Ulrich Lehmann and Juliet M. Daniel and Paul J van Diest and Patrick W B Derksen},
  booktitle={PloS one},
  year={2012}
}
Kaiso is a BTB/POZ transcription factor that is ubiquitously expressed in multiple cell types and functions as a transcriptional repressor and activator. Little is known about Kaiso expression and localization in breast cancer. Here, we have related pathological features and molecular subtypes to Kaiso expression in 477 cases of human invasive breast cancer. Nuclear Kaiso was predominantly found in invasive ductal carcinoma (IDC) (p = 0.007), while cytoplasmic Kaiso expression was linked to… CONTINUE READING
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