Nuclear Import of Histone H2a and H2b Is Mediated by a Network of Karyopherins

@article{Mosammaparast2001NuclearIO,
  title={Nuclear Import of Histone H2a and H2b Is Mediated by a Network of Karyopherins},
  author={Nima Mosammaparast and Kelley R. Jackson and Y X Guo and Cynthia J. Brame and Jeffrey Shabanowitz and Donald F. Hunt and Lucy F. Pemberton},
  journal={The Journal of Cell Biology},
  year={2001},
  volume={153},
  pages={251 - 262}
}
The first step in the assembly of new chromatin is the cell cycle-regulated synthesis and nuclear import of core histones. The core histones include H2A and H2B, which are assembled into nucleosomes as heterodimers. We show here that the import of histone H2A and H2B is mediated by several members of the karyopherin (Kap; importin) family. An abundant complex of H2A, H2B, and Kap114p was detected in cytosol. In addition, two other Kaps, Kap121p and Kap123p, and the histone chaperone Nap1p were… CONTINUE READING

Citations

Publications citing this paper.
SHOWING 1-10 OF 63 CITATIONS, ESTIMATED 77% COVERAGE

FILTER CITATIONS BY YEAR

2001
2019

CITATION STATISTICS

  • 8 Highly Influenced Citations

References

Publications referenced by this paper.
SHOWING 1-10 OF 54 REFERENCES

Crystal structure of the nucleosome core particle at 2.8 A resolution

  • K. Luger, A. W. Mader, R. K. Richmond, D. F. Sargent, T. J. Richmond
  • 1997
Highly Influential
6 Excerpts