Nuclear Gene Sequences from a Late Pleistocene Sloth Coprolite

@article{Poinar2003NuclearGS,
  title={Nuclear Gene Sequences from a Late Pleistocene Sloth Coprolite},
  author={Hendrik N Poinar and Melanie Kuch and Gregory McDonald and Paul Martin and Svante P{\"a}{\"a}bo},
  journal={Current Biology},
  year={2003},
  volume={13},
  pages={1150-1152}
}
The determination of nuclear DNA sequences from ancient remains would open many novel opportunities such as the resolution of phylogenies, the sexing of hominid and animal remains, and the characterization of genes involved in phenotypic traits. However, to date, single-copy nuclear DNA sequences from fossils have been determined only from bones and teeth of woolly mammoths preserved in the permafrost. Since the best preserved ancient nucleic acids tend to stem from cold environments, this has… CONTINUE READING
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