Nuclear Gene Indicates Coat-Color Polymorphism in Mammoths

@article{Rmpler2006NuclearGI,
  title={Nuclear Gene Indicates Coat-Color Polymorphism in Mammoths},
  author={Holger R{\"o}mpler and Nadin Rohland and C. Lalueza-Fox and E. Willerslev and T. Kuznetsova and G. Rabeder and J. Bertranpetit and T. Sch{\"o}neberg and M. Hofreiter},
  journal={Science},
  year={2006},
  volume={313},
  pages={62 - 62}
}
By amplifying the melanocortin type 1 receptor from the woolly mammoth, we can report the complete nucleotide sequence of a nuclear-encoded gene from an extinct species. We found two alleles and show that one allele produces a functional protein whereas the other one encodes a protein with strongly reduced activity. This finding suggests that mammoths may have been polymorphic in coat color, with both dark- and light-haired individuals co-occurring. 
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