Nuclear GPCRs in cardiomyocytes: an insider's view of β-adrenergic receptor signaling.


In recent years, we have come to appreciate the complexity of G protein-coupled receptor signaling in general and β-adrenergic receptor (β-AR) signaling in particular. Starting originally from three β-AR subtypes expressed in cardiomyocytes with relatively simple, linear signaling cascades, it is now clear that there are large receptor-based networks which… (More)
DOI: 10.1152/ajpheart.00657.2011


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