Nuclear Factor I-C acts as a regulator of hepatocyte proliferation at the onset of liver regeneration.

Abstract

BACKGROUND & AIMS Knockout studies of the murine Nuclear Factor I-C (NFI-C) transcription factor revealed abnormal skin wound healing and growth of its appendages, suggesting a role in controlling cell proliferation in adult regenerative processes. Liver regeneration following partial hepatectomy (PH) is a well-established regenerative model whereby changes… (More)
DOI: 10.1111/liv.12697

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