Nuclear Factor-κB Signature of Inflammatory Breast Cancer by cDNA Microarray Validated by Quantitative Real-time Reverse Transcription-PCR, Immunohistochemistry, and Nuclear Factor-κB DNA-Binding

@article{Laere2006NuclearFS,
  title={Nuclear Factor-κB Signature of Inflammatory Breast Cancer by cDNA Microarray Validated by Quantitative Real-time Reverse Transcription-PCR, Immunohistochemistry, and Nuclear Factor-κB DNA-Binding},
  author={S. V. Van Laere and I. Van der Auwera and G. G. Van den Eynden and H. Elst and J. Weyler and A. Harris and P. V. van Dam and E. V. Van marck and P. Vermeulen and L. Dirix},
  journal={Clinical Cancer Research},
  year={2006},
  volume={12},
  pages={3249 - 3256}
}
  • S. V. Van Laere, I. Van der Auwera, +7 authors L. Dirix
  • Published 2006
  • Biology
  • Clinical Cancer Research
  • Purpose: Inflammatory breast cancer (IBC) is the most aggressive form of locally advanced breast cancer with high metastatic potential. In a previous study, we showed that IBC is a different form of breast cancer compared with non-IBC by cDNA microarray analysis. A list of 756 genes with significant expression differences between IBC and non-IBC was identified. In-depth functional analysis revealed the presence of a high number of nuclear factor-κB (NF-κB) target genes with elevated expression… CONTINUE READING
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